Ligand Selectivity and Affinity of Chemokine Receptor CXCR1
نویسندگان
چکیده
منابع مشابه
Structural basis of chemokine receptor function--a model for binding affinity and ligand selectivity.
Chemokine receptors play fundamental roles in human physiology from embryogenesis to inflammatory response. The receptors belong to the G-protein coupled receptor class, and are activated by chemokine ligands with a range of specificities and affinities that result in a complicated network of interactions. The molecular basis for function is largely a black box, and can be directly attributed t...
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ژورنال
عنوان ژورنال: Journal of Biological Chemistry
سال: 2004
ISSN: 0021-9258
DOI: 10.1074/jbc.m313883200